MISSINGNESS ADAPTED GROUP INFORMED CLUSTERED (MAGIC)-LASSO: A NOVEL PARADIGM FOR PHENOTYPE PREDICTION TO IMPROVE POWER FOR GENETIC LOCI DISCOVERY

Missingness adapted group informed clustered (MAGIC)-LASSO: a novel paradigm for phenotype prediction to improve power for genetic loci discovery

Introduction: The availability of large-scale biobanks linking genetic data, rich phenotypes, and biological measures is a powerful opportunity for scientific discovery.However, real-world collections frequently have extensive missingness.While missing data prediction is possible, performance is significantly impaired by block-wise missingness inhe

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(MIS)Translating U.S. Southwest History

Historians of the U.S.Southwest invariably rely on English-language translations of original Spanish documents for their interpretive work.However, a philological approach to the Spanish documents reveals all manner of 3 Piece Dinette translator shortcomings, some of which negatively impact the historical record.I document one such instance pertain

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Evolutionary genomics of LysM genes in land plants

Abstract Background The ubiquitous LysM motif recognizes peptidoglycan, chitooligosaccharides (chitin) and, presumably, other structurally-related oligosaccharides.LysM-containing proteins were first shown to be involved in bacterial cell wall degradation and, more recently, were implicated in perceiving chitin (one of the established pathogen-asso

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Sub-TeV quintuplet minimal dark matter with left-right symmetry

Abstract A detailed study of a fermionic quintuplet dark matter in a left-right symmetric scenario is performed in this article.The minimal quintuplet dark matter model is highly Source Naturals constrained from the WMAP dark matter relic density (RD) data.To elevate this constraint, an extra singlet scalar is introduced.It introduces a host of new

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